Katie uses cryo-ET to reveal kinetochore features in human mitotic chromosomes! (link)
- 1/23/2025
Yi-Wei joins Chan Zuckerberg Initiative Neuroscience Investigators!
- 1/22/2025
Leon won the Ruth Keris Award for Departmental Service!
This annual award recognizes Leon’s above-and-beyond service and leadership in the community of the Department of Biochemistry & Biophysics and the BBCB graduate group.
- 12/6/2024
The lab at the 2024 Biochemistry Biophysics and Chemical Biology retreat.
- 12/6/2024
Lab outing!
- 5/10/2024
Katie won 2024 Saul Winegrad Award for Outstanding Dissertation!
The Award was established in 1995 in honor of the founding Director of Biomedical Graduate Study at Penn, Saul Winegrad, MD, Emeritus Professor of Physiology. The award was created to recognize a dissertation of outstanding quality which makes a significant contribution to biomedical science.
- 4/25/2024
Congratulations to our new Dr. Martinez!
- 4/11/2024
Ben and Katie realized cryo-ET imaging of human brain tissue vitrified directly from autopsy! (link)
- 3/26/2024
Congratulations to our new Dr. Kixmoeller!
- 3/22/2024
Congratulations to our new Dr. Creekmore!
- 3/21/2024
Our new paper from the collaborative project with the Soldati lab is featured in the Editor’s Highlights of Nature Communications!
- 3/20/2024
Katie won John G. Clark Prize!
2024 Medical Student Research Paper Prize Competition
Title: Visualization of human kinetochores by cryo-electron tomography
3/15/2024
Ben won Neurosurgery Research Prize!
2024 Medical Student Research Paper Prize Competition
Title: Ultrastructure of human brain tissue vitrified directly from autopsy revealed by cryo-electron tomography with cryo-plasma focused ion beam milling
3/15/2024
The lab at the 2023 Biochemistry and Molecular Biophysics retreat.
Ruchao received the Mildred Cohn Distinguished Postdoctoral Award!
- 9/1/2023
Matt received the Blavatnik Family Fellowship in Biomedical Research!
- 9/1/2023
Our new work led by Matt and Shrawan using cryo-ET to investigate actin filaments in apicomplexan parasites has allowed us to learn where do these filaments originate at the cell tip and how they could be managed down the cell body to power motility! (link)
- 8/9/2023
Yi-Wei is appointed Associate Director of the new Institute of Structural Biology at Penn
Led by Prof. Vera Moiseenkova-Bell, the new Institute will integrate and expand the extensive structural biology resources and expertise across the campus to maximize their impact in research, education, and medicine.
- 7/1/2023
- 5/19/2023
(VIDEO) Structural Biology at Penn - Bringing the language of life into focus
Leon won NIH F31 fellowship!!
- 3/30/2023
Leon’s work using single particle cryo-ET to visualize dynamic changes in DNA organization of transcription pre-initiation complexes on a divergent promoter is published!! (link)
- 2/1/2023
Matt won the 2022 P. Leslie Dutton Award for Outstanding Publication by a BMB student!
and delivered a wonderful award presentation at the BMB annual retreat!
- 2022/12/2
Matt giving an amazing talk at the Molecular Parasitology Meeting 2022!
- 2022/09/22
Ben won NIH F30 dual-degree fellowship!!
- 8/19/2022
Liam is joining Harvard for his PhD!
Congratulations to our long-term, super-productive undergraduate student Liam Theveny! We can’t wait to see all the amazing things Liam will be doing at Harvard!
- Summer 2022
Billy is going to Caltech for his PhD!
Congratulations to our inaugural lab member William (Billy) Chen! After spending the entire undergraduate time in our lab and made countless contributions, Billy is going to Caltech and blow everyone there away!
- Summer 2022
Matt showcasing cryo-EM sample preparation for visiting high school students
- 07/20/2022
Matt’s work resolving the in situ structure and activities of the rhoptry secretory apparatus in the malaria parasite Plasmodium falciparum is published! (link)
- 7/11/2022
Lab BBQ party at Yi-Wei’s
- 4/24/2022
We are on the journal cover!! (link to the issue)
- 5/2022
Yi-Wei joins the EMBO Journal Catalysts Program, aiming to stimulate innovations among different scientific fields and to advance scientific publishing workflows, policies and inclusiveness. (link)
- 3/1/2022
Matt won the inaugural Martin and Pamela Winter Infectious Disease Fellowship!!
- 02/24/2022
Liam and Shrawan’s great review on how the latest cryo-ET technologies are advancing in situ structural parasitology research!
- 2/8/2022
Secret Santa 2021
- 12/16/2021
Yi-Wei led the team to win the Beckman Foundation 2022 FIB-Milling Sample Preparation for Cellular CryoET Award! (link)
This will enable the acquisition of a cutting-edge cryo-focused ion beam instrument for cryo-ET sample preparation and beyond!
- 12/6/2021
Shrawan won the annual
S. Walter Englander Award for Postdoctoral Research at Penn!!
- 10/29/2021
Shrawan and Amandine presenting their beautiful works at the Molecular Parasitology Meeting XXXII!
- 10/5/2021
In-person lab meeting after 1.5yr!
- 9/20/2021
Amazing work led by Shrawan providing new structural and mechanistic insights into the apicomplexan rhoptry secretion system! (link)
- 8/17/2021
Ben is appointed to the Structural Biology & Molecular Biophysics T32 training program!
- 7/5/2021
Ben’s reviews are on the journal cover! (link)
- 6/16/2021
Celebrating for Ben, Katie, Matt, and Leon passed their PhD candidacy exams together in the span of 1 week!
- 5/11/2021
Ben’s new back-to-back review articles on how cryo-EM has provided new insights into proteostasis factors and aggregates in neurodegenerative diseases!
- 4/17/2021 & 5/10/2021
Katie won NIH F30 dual-degree fellowship!!
- 2/17/2021
A fantastic collaboration with the Lebrun, Turkewitz, and Striepen labs!
- 1/25/2021
Hiking, 2020 style
@ Ridley Park
- 9/19/2020
Virtual lab meeting
- 5/2020
“Yi-Wei named Packard Fellow!”
Yi-Wei and team won the ASPIRE Award from the Mark Foundation for Cancer Research to combine cutting-edge computational analyses with in situ cryo-ET to study cancer biology! (link)
YEAR 1
- 8/6/2019
First
cryo-ET session
- 7/24/2019
Spring 2019
- 6/4/2019
First lab meeting
- 6/4/2019
DAY 1
- 8/6/2018